BDBM50334870 6-bromo-3-(furan-3-yl)-5-(piperidin-3-yl)pyrazolo[1,5-a]pyrimidin-7-amine::CHEMBL1643224

SMILES Nc1c(Br)c(nc2c(cnn12)-c1ccoc1)C1CCCNC1

InChI Key InChIKey=UUXLORHYMYNKFC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50334870   

TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50334870(6-bromo-3-(furan-3-yl)-5-(piperidin-3-yl)pyrazolo[...)
Affinity DataIC50:  25nMAssay Description:Inhibition of histidine-tagged recombinant CHK1 expressed in baculovirus expression system after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed